Anti-CCP (Rheumatoid Factor)
Also called: Anti-Cyclic Citrullinated Peptide, ACPA
Highly specific test for rheumatoid arthritis — positive years before joint damage shows up.
- Duration
- 5 min
- Report
- 48 hours
- Sample
- Blood
- Fasting
- Not needed
What this test is
Anti-CCP antibodies are highly specific for rheumatoid arthritis — much more so than the older rheumatoid factor (RF). They can be positive years before joints are visibly damaged, allowing early treatment that prevents permanent deformity. Ordered when joint pain and swelling suggest an autoimmune cause.
When you need this test
- Symmetric joint pain and swelling (especially hand joints)
- Morning stiffness lasting more than 1 hour
- Family history of rheumatoid arthritis
- Confirmation when rheumatoid factor (RF) is positive
How to prepare
- No fasting required.
- Mention all current arthritis medications and recent steroid use.
Why DiagnoHouse for this test
NABL-accredited lab
Quality-audited blood, urine, and stool analysis.
Home collection
Free across Pimpri-Chinchwad. Sample picked up at your time slot.
Same-day reports
Most pathology reports ready within 4 hours of collection.
Calibrated equipment
Analysers calibrated daily; quality controls run with every batch.
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FAQs
Is this same as Rheumatoid Factor (RF)?
No — anti-CCP is more specific. RF can be positive in many other conditions (chronic infections, other autoimmune diseases). Anti-CCP positive strongly suggests rheumatoid arthritis.Why is early diagnosis important?
Joint damage from rheumatoid arthritis is permanent. Early aggressive treatment with disease-modifying drugs prevents most damage.
Need help choosing?
Not sure if this is the right test for you? Have a doctor's note? Call or WhatsApp — guidance is free.
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